Structural and Functional Analysis of human lung cancer risk associated hOGG1 variant Ser326Cys in DNA repair gene by molecular dynamics simulation

Oxidative damaged DNA base lesions are repaired through human 8-oxoguanine DNA glycosylase gene (hOGG1) mediated pathways. A recent report based on the meta-analysis has suggested that the DNA Repair Gene hOGG1 variant Ser326Cys [3p26.2; allele S/C in nucleotide position αHelix2 Ser⇒Cys326] was asso...

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Bibliographic Details
Main Author: Zainularifeen Abduljaleel
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2019-09-01
Series:Non-coding RNA Research
Online Access:http://www.sciencedirect.com/science/article/pii/S2468054019300290