SHISA3, an antagonist of the Wnt/β-catenin signaling, is epigenetically silenced and its ectopic expression suppresses growth in breast cancer.

SHISA3, an antagonist of the Wnt/β-catenin signaling, is epigenetically silenced and its ectopic expression suppresses growth in breast cancer.

Breast cancer (BC) is the foremost cause of cancer related deaths in women globally. Currently there is a scarcity of reliable biomarkers for its early stage diagnosis and theranostics monitoring. Altered DNA methylation patterns leading to the silencing of tumor suppressor genes are considered as a...

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Bibliographic Details
Main Authors: Naveed Shahzad, Tehreem Munir, Mariam Javed, Fareeda Tasneem, Bilal Aslam, Moazzam Ali, Zeeshan Mutahir, Muhammad Akhtar Ali, Muhammad Umer, Munir Ahmad, Kokab Farooq, Umair Hassan, Tanveer Mustafa, Rana Salman Anjum, Abdul Rauf Shakoori
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0236192

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https://doi.org/10.1371/journal.pone.0236192

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