Exploiting vulnerabilities of cancer by targeting nuclear receptors of stromal cells in tumor microenvironment

Exploiting vulnerabilities of cancer by targeting nuclear receptors of stromal cells in tumor microenvironment

Abstract The tumor microenvironment is a complex and dynamic cellular community comprising the tumor epithelium and various tumor-supporting cells such as immune cells, fibroblasts, immunosuppressive cells, adipose cells, endothelial cells, and pericytes. The interplay between the tumor microenviron...

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Bibliographic Details
Main Authors: Hong Sheng Cheng, Jeannie Xue Ting Lee, Walter Wahli, Nguan Soon Tan
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Molecular Cancer
Subjects:
Nuclear receptors
Tumor microenvironment
Cancer-associated fibroblast
Myeloid-derived suppressor cells
Tumor-associated macrophage
Online Access:http://link.springer.com/article/10.1186/s12943-019-0971-9

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http://link.springer.com/article/10.1186/s12943-019-0971-9

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