SET-9 and SET-26 are H3K4me3 readers and play critical roles in germline development and longevity

C. elegans SET-9 and SET-26 are highly homologous paralogs that share redundant functions in germline development, but SET-26 alone plays a key role in longevity and heat stress response. Whereas SET-26 is broadly expressed, SET-9 is only detectable in the germline, which likely accounts for their d...

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Bibliographic Details
Main Authors: Wenke Wang, Amaresh Chaturbedi, Minghui Wang, Serim An, Satheeja Santhi Velayudhan, Siu Sylvia Lee
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/34970