Citrate Supplementation Restores the Impaired Mineralisation Resulting from the Acidic Microenvironment: An In Vitro Study

Chronic metabolic acidosis leads to bone-remodelling disorders based on excessive mineral matrix resorption and inhibition of bone formation, but also affects the homeostasis of citrate, which is an essential player in maintaining the acid–base balance and in driving the mineralisation process. This...

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Bibliographic Details
Main Authors: Francesca Perut, Gabriela Graziani, Marta Columbaro, Renata Caudarella, Nicola Baldini, Donatella Granchi
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/12/12/3779