Development of an efficient targeted cell-SELEX procedure for DNA aptamer reagents.

Development of an efficient targeted cell-SELEX procedure for DNA aptamer reagents.

DNA aptamers generated by cell-SELEX offer an attractive alternative to antibodies, but generating aptamers to specific, known membrane protein targets has proven challenging, and has severely limited the use of aptamers as affinity reagents for cell identification and purification.We modified the B...

Full description

Bibliographic Details
Main Authors: Susanne Meyer, John P Maufort, Jeff Nie, Ron Stewart, Brian E McIntosh, Lisa R Conti, Kareem M Ahmad, H Tom Soh, James A Thomson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3742456?pdf=render

Internet

http://europepmc.org/articles/PMC3742456?pdf=render

Similar Items