Thermal stability of the human immunodeficiency virus type 1 (HIV-1) receptors, CD4 and CXCR4, reconstituted in proteoliposomes.

Thermal stability of the human immunodeficiency virus type 1 (HIV-1) receptors, CD4 and CXCR4, reconstituted in proteoliposomes.

The entry of human immunodeficiency virus (HIV-1) into host cells involves the interaction of the viral exterior envelope glycoprotein, gp120, and receptors on the target cell. The HIV-1 receptors are CD4 and one of two chemokine receptors, CCR5 or CXCR4.We created proteoliposomes that contain CD4,...

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Bibliographic Details
Main Authors: Mikhail A Zhukovsky, Stéphane Basmaciogullari, Beatriz Pacheco, Liping Wang, Navid Madani, Hillel Haim, Joseph Sodroski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2954141?pdf=render

Internet

http://europepmc.org/articles/PMC2954141?pdf=render

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