The chemopreventive retinoid 4HPR impairs prostate cancer cell migration and invasion by interfering with FAK/AKT/GSK3β pathway and β-catenin stability

<p>Abstract</p> <p>Background</p> <p>Prostate cancer shows an extremely slow progression, appearing in its metastatic, hormone refractory phenotype mostly in elderly men. The chemopreventive targeting of this tumor could accordingly delay its malignancy over life expect...

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Bibliographic Details
Main Authors: Tosetti Francesca, Venè Roberta, Monteghirfo Stefano, Benelli Roberto, Ferrari Nicoletta
Format: Article
Language:English
Published: BMC 2010-06-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/142