Chondroitin 6-Sulfation Regulates Perineuronal Net Formation by Controlling the Stability of Aggrecan
Perineuronal nets (PNNs) are lattice-like extracellular matrix structures composed of chondroitin sulfate proteoglycans (CSPGs). The appearance of PNNs parallels the decline of neural plasticity, and disruption of PNNs reactivates neural plasticity in the adult brain. We previously reported that sul...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2016-01-01
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Series: | Neural Plasticity |
Online Access: | http://dx.doi.org/10.1155/2016/1305801 |