LGP2 expression is enhanced by interferon regulatory factor 3 in olive flounder, Paralichthys olivaceus.

In innate immunity, LGP2 (laboratory of genetics and physiology 2) plays a very important role in the production of type I interferon (IFN) through recognition of cytosolic viral RNA. Although viral infection or stimulation with double-strand RNA dramatically induces expression of the LGP2 gene, the...

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Bibliographic Details
Main Authors: Jun-Ichi Hikima, Mi-Kyong Yi, Maki Ohtani, Chan Yong Jung, Young Kyu Kim, Ji Young Mun, Young Rim Kim, Haruko Takeyama, Takashi Aoki, Tae Sung Jung
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3519686?pdf=render