Accurate Classification of Differential Expression Patterns in a Bayesian Framework With Robust Normalization for Multi-Group RNA-Seq Count Data
Empirical Bayes is a choice framework for differential expression (DE) analysis for multi-group RNA-seq count data. Its characteristic ability to compute posterior probabilities for predefined expression patterns allows users to assign the pattern with the highest value to the gene under considerati...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2019-07-01
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Series: | Bioinformatics and Biology Insights |
Online Access: | https://doi.org/10.1177/1177932219860817 |