Accurate Classification of Differential Expression Patterns in a Bayesian Framework With Robust Normalization for Multi-Group RNA-Seq Count Data

Empirical Bayes is a choice framework for differential expression (DE) analysis for multi-group RNA-seq count data. Its characteristic ability to compute posterior probabilities for predefined expression patterns allows users to assign the pattern with the highest value to the gene under considerati...

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Bibliographic Details
Main Authors: Takayuki Osabe, Kentaro Shimizu, Koji Kadota
Format: Article
Language:English
Published: SAGE Publishing 2019-07-01
Series:Bioinformatics and Biology Insights
Online Access:https://doi.org/10.1177/1177932219860817