Depletion of alveolar macrophages ameliorates virus-induced disease following a pulmonary coronavirus infection.

Coronaviruses cause respiratory disease in humans that can range from mild to severe. However, the pathogenesis of pulmonary coronavirus infections is poorly understood. Mouse hepatitis virus type 1 (MHV-1) is a group 2 coronavirus capable of causing severe morbidity and mortality in highly suscepti...

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Bibliographic Details
Main Authors: Stacey M Hartwig, Kaitlyn M Holman, Steven M Varga
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3946553?pdf=render