Co-delivery of Dacarbazine and All-Trans Retinoic Acid (ATRA) Using Lipid Nanoformulations for Synergistic Antitumor Efficacy Against Malignant Melanoma

Co-delivery of Dacarbazine and All-Trans Retinoic Acid (ATRA) Using Lipid Nanoformulations for Synergistic Antitumor Efficacy Against Malignant Melanoma

Abstract Malignant melanoma is a highly aggressive skin cancer responsible for 80% of mortality, and the overall median survival in patients with metastatic melanoma is only 6–9 months. Combination treatment through the simultaneous administration of dual drugs in a single nanocarrier has been demon...

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Bibliographic Details
Main Authors: Chenyang Li, Xiuping Han
Format: Article
Language:English
Published: SpringerOpen 2020-05-01
Series:Nanoscale Research Letters
Subjects:
Melanoma
Dacarbazine
All-trans retinoic acid (ATRA)
Lipid nanoformulations
Combination therapy
Online Access:http://link.springer.com/article/10.1186/s11671-020-3293-3

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http://link.springer.com/article/10.1186/s11671-020-3293-3

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