Temporal colonic gene expression profiling in the recurrent colitis model identifies early and chronic inflammatory processes.

The recurrent TNBS-colitis model in BALB/c mice has been proposed as a model of Inflammatory Bowel Disease with a shifting pattern of local cytokines with the expression of Th1 cytokines during the early phase, Th17 cytokines during the intermediate phase and Th2 cytokines during late fibrotic stage...

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Bibliographic Details
Main Authors: Bas Kremer, Rob Mariman, Marjan van Erk, Tonny Lagerweij, Lex Nagelkerken
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3511545?pdf=render