Analysis of neurogenesis during experimental autoimmune encephalomyelitis reveals pitfalls of bioluminescence imaging.

Bioluminescence imaging is a sensitive approach for longitudinal neuroimaging. Transgenic mice expressing luciferase under the promoter of doublecortin (DCX-luc), a specific marker of neuronal progenitor cells (NPC), allow monitoring of neurogenesis in living mice. Since the extent and time course o...

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Bibliographic Details
Main Authors: Ilya Ayzenberg, Sibylle Schlevogt, Judith Metzdorf, Sarah Stahlke, Xiomara Pedreitturia, Anika Hunfeld, Sebastien Couillard-Despres, Ingo Kleiter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4363373?pdf=render