Cerebrospinal fluid biomarkers for Alzheimer's disease in Down syndrome

Abstract Down syndrome (DS), present in nearly six million people, is associated with an extremely high risk to develop Alzheimer's disease (AD). Amyloid‐β and tau pathology are omnipresent from age 40 years onward, but clinical symptoms do not appear in all DS individuals. Dementia diagnostics...

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Bibliographic Details
Main Authors: Alain D. Dekker, Juan Fortea, Rafael Blesa, Peter P. De Deyn
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
Online Access:https://doi.org/10.1016/j.dadm.2017.02.006