Scope and limitations of a DMF bio-alternative within Sonogashira cross-coupling and Cacchi-type annulation
Pd-catalysed C–C bond formation is an essential tool within the pharmaceutical and agrochemical industries. Many of these reactions rely heavily on polar aprotic solvents; however, despite their utility, these solvents are incompatible with the drive towards more sustainable chemical synthesis. Here...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Beilstein-Institut
2016-09-01
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Series: | Beilstein Journal of Organic Chemistry |
Subjects: | |
Online Access: | https://doi.org/10.3762/bjoc.12.187 |