Scope and limitations of a DMF bio-alternative within Sonogashira cross-coupling and Cacchi-type annulation

Pd-catalysed C–C bond formation is an essential tool within the pharmaceutical and agrochemical industries. Many of these reactions rely heavily on polar aprotic solvents; however, despite their utility, these solvents are incompatible with the drive towards more sustainable chemical synthesis. Here...

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Bibliographic Details
Main Authors: Kirsty L. Wilson, Alan R. Kennedy, Jane Murray, Ben Greatrex, Craig Jamieson, Allan J. B. Watson
Format: Article
Language:English
Published: Beilstein-Institut 2016-09-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.12.187