Canine Models for Copper Homeostasis Disorders

Canine Models for Copper Homeostasis Disorders

Copper is an essential trace nutrient metal involved in a multitude of cellular processes. Hereditary defects in copper metabolism result in disorders with a severe clinical course such as Wilson disease and Menkes disease. In Wilson disease, copper accumulation leads to liver cirrhosis and neurolog...

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Bibliographic Details
Main Authors:	Xiaoyan Wu, Peter A. J. Leegwater, Hille Fieten
Format:	Article
Language:	English
Published:	MDPI AG 2016-02-01
Series:	International Journal of Molecular Sciences
Subjects:	copper toxicosis nutrition genetics Wilson disease Menkes disease ATP7A ATP7B COMMD1 Bedlington terrier Labrador retriever
Online Access:	http://www.mdpi.com/1422-0067/17/2/196

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