The Actin-Bundling Protein L-Plastin: A Critical Regulator of Immune Cell Function
L-plastin is a leukocyte-specific protein that cross-links actin filaments into tight bundles, increasing the stability of actin-based structures such as podosomes and lamellipodia. While first identified as an abundant cytoplasmic protein in hematopoietically derived cells over 25 years ago, the re...
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2012-01-01
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Series: | International Journal of Cell Biology |
Online Access: | http://dx.doi.org/10.1155/2012/935173 |