Targeted Delivery of Amoxicillin to C. trachomatis by the Transferrin Iron Acquisition Pathway.

Weak intracellular penetration of antibiotics makes some infections difficult to treat. The Trojan horse strategy for targeted drug delivery is among the interesting routes being explored to overcome this therapeutic difficulty. Chlamydia trachomatis, as an obligate intracellular human pathogen, is...

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Bibliographic Details
Main Authors: Jun Hai, Nawal Serradji, Ludovic Mouton, Virginie Redeker, David Cornu, Jean-Michel El Hage Chahine, Philippe Verbeke, Miryana Hémadi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4768884?pdf=render