Target Analysis and Mechanism of Podophyllotoxin in the Treatment of Triple-Negative Breast Cancer

Target Analysis and Mechanism of Podophyllotoxin in the Treatment of Triple-Negative Breast Cancer

BackgroundAs the original compound of many podophyllotoxin derivatives, podophyllotoxin has a beneficial antitumor effect. The mechanism of podophyllotoxin activity in triple-negative breast cancer still needs to be explored.MethodsWe used cell proliferation assay, scratch and transwell experiments,...

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Bibliographic Details
Main Authors: Wenfeng Zhang, Cun Liu, Jie Li, Ruijuan Liu, Jing Zhuang, Fubin Feng, Yan Yao, Changgang Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Pharmacology
Subjects:
breast cancer
cell cycle
inhibition
network pharmacology
podophyllotoxin
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01211/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.01211/full

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