NADPH oxidase Nox1 contributes to ischemic injury in experimental stroke in mice

NADPH oxidase Nox1 contributes to ischemic injury in experimental stroke in mice

Reactive oxygen species (ROS) are mediators of brain injury in ischemia/reperfusion. An involvement of the NADPH oxidase Nox2 has been demonstrated. In contrast, only little is known about the contribution of the Nox1 homologue in this context. Thus, we studied the role of Nox1 in early cerebral rep...

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Bibliographic Details
Main Authors: Timo Kahles, Andreas Kohnen, Sabine Heumueller, Angelika Rappert, Ingo Bechmann, Stefan Liebner, Ina M. Wittko, Tobias Neumann-Haefelin, Helmuth Steinmetz, Katrin Schroeder, Ralf P. Brandes
Format: Article
Language:English
Published: Elsevier 2010-10-01
Series:Neurobiology of Disease
Subjects:
Stroke
Reperfusion
NADPH Oxidase
Nox1
Blood–brain barrier
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996110001853

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http://www.sciencedirect.com/science/article/pii/S0969996110001853

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