Role of MRP-1 and GST-Pi in MDR and their inhibition by indomethacin in AML

Background: MDR continues to be a major challenge to effective chemotherapeutic interventions against cancer. Defining major factor contributing to MDR and inhibiting their action may thus be used for reversing MDR. Aim: This work aimed to evaluate the role played by MRP-1 and GST-Pi in MDR, and to...

Full description

Bibliographic Details
Main Authors: Samia A. Ebeed, Nadia A. Sadek, Ebtsam R. Zaher, Mervat M. Mahmoud, Gihan Nabil, Sanaa A. Elbenhawy
Format: Article
Language:English
Published: Taylor & Francis Group 2017-08-01
Series:Alexandria Journal of Medicine
Subjects:
AML
MDR
Online Access:http://www.sciencedirect.com/science/article/pii/S2090506816300276