Inhibitory Effects of Pteridines on the Cytochrome P-450 Enzyme System

Inhibitory Effects of Pteridines on the Cytochrome P-450 Enzyme System

The effects of 17 different pteridine derivatives on rat liver microsomal cytochrome P-450 catalyzed degradation of aminoantipyrin were studied. Neopterin (41% of control), biopterin (42%), monapterin (73%), pterin (74%), lumazine (75%) and 6-methylpterin (77%) significantly inhibit the degradation...

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Bibliographic Details
Main Authors: Horejsi Renate, Daczki Jürgen, Mölller Reinhard, Öttl Karl, Vrecko Karoline, Reibnegger Gilbert
Format: Article
Language:English
Published: De Gruyter 1997-01-01
Series:Pteridines
Subjects:
cytochrome p -450
rat liver microsomes
pteridine derivatives
molecular structure
aminoantipyrin degradation
Online Access:https://doi.org/10.1515/pteridines.1997.8.1.21

Internet

https://doi.org/10.1515/pteridines.1997.8.1.21

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