Myocyte [Na+]i Dysregulation in Heart Failure and Diabetic Cardiomyopathy
By controlling the function of various sarcolemmal and mitochondrial ion transporters, intracellular Na+ concentration ([Na+]i) regulates Ca2+ cycling, electrical activity, the matching of energy supply and demand, and oxidative stress in cardiac myocytes. Thus, maintenance of myocyte Na+ homeostasi...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2018-09-01
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Series: | Frontiers in Physiology |
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Online Access: | https://www.frontiersin.org/article/10.3389/fphys.2018.01303/full |