DNA Methylation Profiling Reveals the Change of Inflammation-Associated ZC3H12D in Leukoaraiosis

DNA Methylation Profiling Reveals the Change of Inflammation-Associated ZC3H12D in Leukoaraiosis

Leukoaraiosis (LA) is neuroimaging abnormalities of the cerebral white matter in elderly people. However, the molecular mechanisms underlying the cerebral white matter lesions remain unclear. Here, we reported an epigenetic basis and potential pathogenesis for this complex illness. 317 differentiall...

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Bibliographic Details
Main Authors: Wen-Qing Huang, Ke-Hui Yi, Zhi Li, Han Wang, Ming-Li Li, Liang-Liang Cai, Hui-Nuan Lin, Qing Lin, Chi-Meng Tzeng
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
demyelination
leukoaraiosis (LA)
methylation
neuroinflammation
white matter lesions (WML)
ZC3H12D
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00143/full

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https://www.frontiersin.org/article/10.3389/fnagi.2018.00143/full

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