Heme Oxygenase-1 May Affect Cell Signalling via Modulation of Ganglioside Composition

Heme oxygenase 1 (Hmox1), a ubiquitous enzyme degrading heme to carbon monoxide, iron, and biliverdin, is one of the cytoprotective enzymes induced in response to a variety of stimuli, including cellular oxidative stress. Gangliosides, sialic acid-containing glycosphingolipids expressed in all cells...

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Bibliographic Details
Main Authors: Václav Šmíd, Jakub Šuk, Neli Kachamakova-Trojanowska, Jana Jašprová, Petra Valášková, Alicja Józkowicz, Józef Dulak, František Šmíd, Libor Vítek, Lucie Muchová
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2018/3845027