Advantages of Single-Molecule Real-Time Sequencing in High-GC Content Genomes.

Next-generation sequencing has become the most widely used sequencing technology in genomics research, but it has inherent drawbacks when dealing with high-GC content genomes. Recently, single-molecule real-time sequencing technology (SMRT) was introduced as a third-generation sequencing strategy to...

Full description

Bibliographic Details
Main Authors: Seung Chul Shin, Do Hwan Ahn, Su Jin Kim, Hyoungseok Lee, Tae-Jin Oh, Jong Eun Lee, Hyun Park
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3720884?pdf=render