Integrated Transcriptomic and Proteomic Analysis of Red Blood Cells from Rainbow Trout Challenged with VHSV Point Towards Novel Immunomodulant Targets

Integrated Transcriptomic and Proteomic Analysis of Red Blood Cells from Rainbow Trout Challenged with VHSV Point Towards Novel Immunomodulant Targets

Teleost red blood cells (RBCs) are nucleated and therefore can propagate cellular responses to exogenous stimuli. RBCs can mount an immune response against a variety of fish viruses, including the viral septicemia hemorrhagic virus (VHSV), which is one of the most prevalent fish viruses resulting in...

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Bibliographic Details
Main Authors: Ivan Nombela, Marina Lopez-Lorigados, Maria Elizabeth Salvador-Mira, Sara Puente-Marin, Veronica Chico, Sergio Ciordia, Maria Carmen Mena, Luis Mercado, Julio Coll, Luis Perez, Maria del Mar Ortega-Villaizan
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Vaccines
Subjects:
erythrocytes
red blood cells
transcriptome
proteome
interferon
complement
VHSV
rhabdoviruses
Mx
IFIT5
β-defensin 1
antigen presentation
Online Access:https://www.mdpi.com/2076-393X/7/3/63

Internet

https://www.mdpi.com/2076-393X/7/3/63

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