Quantifying insulin sensitivity and entero-insular responsiveness to hyper- and hypoglycemia in ferrets.

Ferrets are an important emerging model of cystic fibrosis related diabetes. However, there is little documented experience in the use of advanced techniques to quantify aspects of diabetes pathophysiology in the ferret. Glycemic clamps are the gold standard technique to assess both insulin sensitiv...

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Bibliographic Details
Main Authors: Hongshu Sui, Yaling Yi, Jianrong Yao, Bo Liang, Xingshen Sun, Shanming Hu, Aliye Uc, Deborah J Nelson, Katie Larson Ode, Louis H Philipson, John F Engelhardt, Andrew W Norris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3940889?pdf=render