Discordancy Partitioning for Validating Potentially Inconsistent Pharmacogenomic Studies
Abstract The Genomics of Drug Sensitivity in Cancer (GDSC) and Cancer Cell Line Encyclopedia (CCLE) are two major studies that can be used to mine for therapeutic biomarkers for cancers of a large variety. Model validation using the two datasets however has proved challenging. Both predictions and s...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2017-11-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-017-15590-4 |