GRP78/BIP/HSPA5 as a Therapeutic Target in Models of Parkinson’s Disease: A Mini Review

Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by selective loss of dopamine neurons in the substantia nigra pars compacta of the midbrain. Reports from postmortem studies in the human PD brain, and experimental PD models reveal that endoplasmic reticulum (ER) stress i...

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Bibliographic Details
Main Authors: Adaze Bijou Enogieru, Sylvester Ifeanyi Omoruyi, Donavon Charles Hiss, Okobi Eko Ekpo
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Advances in Pharmacological Sciences
Online Access:http://dx.doi.org/10.1155/2019/2706783