Central Administration of Insulin Combined With Resistin Reduces Renal Sympathetic Nerve Activity in Rats Fed a High Fat Diet

Central Administration of Insulin Combined With Resistin Reduces Renal Sympathetic Nerve Activity in Rats Fed a High Fat Diet

Insulin receptors are widely distributed in the central nervous system and their activation by insulin elicits renal sympatho-excitatory effects. Resistin, an adipokine, promotes resistance to the metabolic effects of insulin. Resistin also induces increases in renal sympathetic nerve activity (RSNA...

Full description

Bibliographic Details
Main Authors: Hamza Habeeballah, Naif Alsuhaymi, Martin J. Stebbing, Emilio Badoer
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Physiology
Subjects:
resistin
insulin
renal sympathetic nerve activity
high fat diet
central interactions
cardiovascular function
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00093/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.00093/full

Similar Items