TP53 and MDM2 gene polymorphisms, gene-gene interaction, and hepatocellular carcinoma risk: evidence from an updated meta-analysis.

The association between TP53 R72P and/or MDM2 SNP309 polymorphisms and hepatocellular carcinoma (HCC) risk has been widely reported, but results were inconsistent. To clarify the effects of these polymorphisms on HCC risk, an updated meta-analysis of all available studies was conducted.Eligible arti...

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Main Authors: Qiliu Peng, Xianjun Lao, Zhiping Chen, Hao Lai, Yan Deng, Jian Wang, Cuiju Mo, Jingzhe Sui, Junrong Wu, Limin Zhai, Shi Yang, Xue Qin, Shan Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3871586?pdf=render