Human Serum Enhances Biomimicry of Engineered Tissue Models of Bone and Cancer

For decades, fetal bovine serum (FBS) has been used routinely for culturing many cell types, based on its empirically demonstrated effects on cell growth, and the lack of suitable non-xenogeneic alternatives. The FBS-based culture media do not represent the human physiological conditions, and can co...

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Bibliographic Details
Main Authors: Aranzazu Villasante, Samuel T. Robinson, Andrew R. Cohen, Roberta Lock, X. Edward Guo, Gordana Vunjak-Novakovic
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
3Rs
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.658472/full