Irisin Improves Myocardial Performance and Attenuates Insulin Resistance in Spontaneous Mutation (Leprdb) Mice

BackgroundIrisin, a newly identified peptide, is critical to regulating metabolism, thermogenesis, and reducing oxidative stresses. Our recent works demonstrated that irisin protected the heart against myocardial ischemic injury and preserved the function of mitochondria. However, whether irisin pre...

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Bibliographic Details
Main Authors: Jianguo Wang, Yu Tina Zhao, Ling Zhang, Patrycja M. Dubielecka, Shougang Zhuang, Gangjian Qin, Yu Eugene Chin, Shouyan Zhang, Ting C. Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00769/full