Effects of losartan on haemodynamic parameters and angiotensin receptor mRNA levels in rat heart after myocardial infarction

We investigated the haemodynamic parameters and the regulation of cardiac mRNA levels of the angiotensin receptor subtypes, AT 1 and AT 2 , by the AT 1 -receptor antagonist losartan in rat heart during the acute phase of myocardial infarction. AT 1 - and AT 2 -receptor mRNA levels markedly increased...

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Bibliographic Details
Main Authors: Yi Zhun Zhu, Yi-Chun Zhu, Jun Li, Heiner Schäfer, Wolfgang Schmidt, Tai Yao, Thomas Unger
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2000-09-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2000.039