Protein under-wrapping causes dosage sensitivity and decreases gene duplicability.

A fundamental issue in molecular evolution is how to identify the evolutionary forces that determine the fate of duplicated genes. The dosage balance hypothesis has been invoked to explain gene duplication patterns at the genomic level under the premise that a dosage imbalance among protein-complex...

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Bibliographic Details
Main Authors: Han Liang, Kristina Rogale Plazonic, Jianping Chen, Wen-Hsiung Li, Ariel Fernández
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2211539?pdf=render