Enhanced Intradermal Delivery of Nanosuspensions of Antifilariasis Drugs Using Dissolving Microneedles: A Proof of Concept Study

Enhanced Intradermal Delivery of Nanosuspensions of Antifilariasis Drugs Using Dissolving Microneedles: A Proof of Concept Study

Conventional oral administration of antifilariasis drugs results in nonspecific targeting of the drugs and the intradermal delivery of nanoparticles with sizes of <100 nm could be used to improve lymphatic uptake. This study investigated the combination of nanosuspension and dissolving micron...

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Bibliographic Details
Main Authors: Andi Dian Permana, Maelíosa T. C. McCrudden, Ryan F. Donnelly
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Pharmaceutics
Subjects:
doxycycline
albendazole
ivermectin
nanosuspension
microneedles
dermatokinetic
lymphatic filariasis
Online Access:https://www.mdpi.com/1999-4923/11/7/346

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https://www.mdpi.com/1999-4923/11/7/346

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