A Novel Biological Strategy for Myocardial Protection by Intracoronary Delivery of Mitochondria: Safety and Efficacy

A Novel Biological Strategy for Myocardial Protection by Intracoronary Delivery of Mitochondria: Safety and Efficacy

Summary: Mitochondrial dysfunction is the determinant insult of ischemia-reperfusion injury. Autologous mitochondrial transplantation involves supplying one’s healthy mitochondria to the ischemic region harboring damaged mitochondria. The authors used in vivo swine to show that mitochondrial transpl...

Full description

Bibliographic Details
Main Authors: Borami Shin, MD, Mossab Y. Saeed, MD, Jesse J. Esch, MD, Alvise Guariento, MD, David Blitzer, MD, Kamila Moskowitzova, MD, Giovanna Ramirez-Barbieri, MD, Arzoo Orfany, MD, Jerusha K. Thedsanamoorthy, BA, Douglas B. Cowan, PhD, James A. Inkster, PhD, Erin R. Snay, BRS, Steven J. Staffa, MS, Alan B. Packard, PhD, David Zurakowski, PhD, Pedro J. del Nido, MD, James D. McCully, PhD
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:JACC: Basic to Translational Science
Online Access:http://www.sciencedirect.com/science/article/pii/S2452302X19302608

Internet

http://www.sciencedirect.com/science/article/pii/S2452302X19302608

Similar Items