Deep Surveying of the Transcriptional and Alternative Splicing Signatures for Decidual CD8+ T Cells at the First Trimester of Human Healthy Pregnancy

Deep Surveying of the Transcriptional and Alternative Splicing Signatures for Decidual CD8+ T Cells at the First Trimester of Human Healthy Pregnancy

Decidual CD8+ (dCD8) T cells have been proposed to play important roles in immune protection against the invading pathogens and in tolerance toward the growing semi-allogeneic fetus during early pregnancy. However, their phenotypic and functional characteristics remain poorly defined. Here, we perfo...

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Bibliographic Details
Main Authors: Weihong Zeng, Xinmei Liu, Zhicui Liu, Ying Zheng, Tiantian Yu, Shaliu Fu, Xiao Li, Jing Zhang, Siming Zhang, Xiaoling Ma, Xiao-Rui Liu, Xiaoli Qin, Asma Khanniche, Yan Zhang, Fuju Tian, Yi Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
human decidual CD8+ T cells
early healthy pregnancy
transcriptome and alternative splicing
high-throughput mRNA sequencing
functional feature
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00937/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00937/full

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