DUOX1 Silencing in Mammary Cell Alters the Response to Genotoxic Stress

DUOX1 is an H2O2-generating enzyme related to a wide range of biological features, such as hormone synthesis, host defense, cellular proliferation, and fertilization. DUOX1 is frequently downregulated in lung and liver cancers, suggesting a tumor suppressor role for this enzyme. Here, we show that D...

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Bibliographic Details
Main Authors: Rodrigo S. Fortunato, Luciana R. Gomes, Veridiana Munford, Carolina Fittipaldi Pessoa, Annabel Quinet, Fabio Hecht, Gustavo S. Kajitani, Cristiane Bedran Milito, Denise P. Carvalho, Carlos Frederico Martins Menck
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2018/3570526