Pellino1 promoted inflammation in lung injury model of sepsis by TRAF6/ NF-κB signal pathway

Abstract Background This study was designed to investigate the role of Pellino1 in lung injury model of sepsis and its anti-inflammation mechanism. Method: C57BL/6 male mice (6–7 weeks old) and Pellino1−/− male mice were subjected to laparotomy followed by extracorporeal cecum mobilization and ligat...

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Bibliographic Details
Main Authors: Xiaqing Liu, Zhengfang Lin, Yufeng Xu
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Journal of Inflammation
Subjects:
Online Access:https://doi.org/10.1186/s12950-021-00276-6