Neurotoxicity and inflammation induced by individual and combined exposure to iron oxide nanoparticles and silver nanoparticles

Neurotoxicity and inflammation induced by individual and combined exposure to iron oxide nanoparticles and silver nanoparticles

The present study aimed to investigate the neurotoxicity of iron oxide and silver NPs solely or combined. At the molecular level, the exposure to both NPs induced marked DNA fragmentation, downregulation of mtTFA, and upregulation of PGC-1α expression. Both NPs caused decline in acetylcholine estera...

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Bibliographic Details
Main Authors: Mokhtar Ibrahim Yousef, Abdelsalam Abdalla Abuzreda, Maher Abd EL-Nabi Kamel
Format: Article
Language:English
Published: Taylor & Francis Group 2019-12-01
Series:Journal of Taibah University for Science
Subjects:
iron oxide and silver nanoparticles
mitochondrial transcription factor a
peroxisome proliferator activator receptor gamma-coactivator 1α
oxidative stress
Online Access:http://dx.doi.org/10.1080/16583655.2019.1602351

Internet

http://dx.doi.org/10.1080/16583655.2019.1602351

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