Autophagy and apoptosis are regulated by stress on Bcl2 by AMBRA1 in the endoplasmic reticulum and mitochondria

Abstract Background Autophagy and apoptosis are two important physiological processes that determine cell survival or death in response to different stress signals. The regulatory mechanisms of these two processes share B-cell lymphoma-2 family proteins and AMBRA1, which are present in both the endo...

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Bibliographic Details
Main Authors: Bojie Yang, Quansheng Liu, Yuanhong Bi
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Theoretical Biology and Medical Modelling
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12976-019-0113-5