Regulation of lineage specific DNA hypomethylation in mouse trophectoderm.

DNA methylation is reprogrammed during early embryogenesis by active and passive mechanisms in advance of the first differentiation event producing the embryonic and extraembryonic lineage cells which contribute to the future embryo proper and to the placenta respectively. Embryonic lineage cells re...

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Bibliographic Details
Main Authors: Masaaki Oda, David Oxley, Wendy Dean, Wolf Reik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3692478?pdf=render