miR-212/132-Enriched Extracellular Vesicles Promote Differentiation of Induced Pluripotent Stem Cells Into Pancreatic Beta Cells

miR-212/132-Enriched Extracellular Vesicles Promote Differentiation of Induced Pluripotent Stem Cells Into Pancreatic Beta Cells

Pancreatic beta cell transplantation is the ideal method for treatment of type 1 diabetes mellitus (T1DM), and the generation of beta cells from induced pluripotent stem cells (iPSCs) of patients is a promising strategy. In this study, we improved a previous strategy to produce beta cells using extr...

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Bibliographic Details
Main Authors: Chunyu Bai, Qiwei Ren, Haifeng Liu, Xiangchen Li, Weijun Guan, Yuhua Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
iPSCs
beta cells
differentiation
extracellular vesicles
miRNAs
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.673231/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.673231/full

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