A Functional Variant rs6435156C>T in BMPR2 is Associated With Increased Risk of Chronic Obstructive Pulmonary Disease (COPD) in Southern Chinese Population

A Functional Variant rs6435156C>T in BMPR2 is Associated With Increased Risk of Chronic Obstructive Pulmonary Disease (COPD) in Southern Chinese Population

Backgrounds: Bone morphogenetic protein receptor type 2 (BMPR2) signaling is anti-inflammatory. Decreased BMPR2 expression was seen in lung tissue from chronic obstructive pulmonary disease (COPD) patients. Methods: The selected single nucleotide polymorphisms (SNPs) in BMPR2 were genotyped with pol...

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Bibliographic Details
Main Authors: Jian Wang, Chenting Zhang, Zili Zhang, Zeguang Zheng, Dejun Sun, Quan Yang, Cyrus Hadadi, Defu Li, Xiaoming Xu, Mingmei Xiong, Qipeng Zhou, Meihua Guo, Yingfeng Wang, Chun Tang, Guihua Xu, Kai Yang, Nanshan Zhong, Wenju Lu
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:EBioMedicine
Subjects:
COPD
BMPR2
rs6435156
Cigarette smoking
hsa-miR-20a
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416300378

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http://www.sciencedirect.com/science/article/pii/S2352396416300378

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