Toll-like receptor activation enhances cell-mediated immunity induced by an antibody vaccine targeting human dendritic cells

<p>Abstract</p> <p>Previously, we have successfully targeted the mannose receptor (MR) expressed on monocyte-derived dendritic cells (DCs) using a fully human MR-specific antibody, B11, as a vehicle to deliver whole protein tumor antigens such as the human chorionic gonadotropin ho...

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Bibliographic Details
Main Authors: Berger Marc A, Tario Joseph D, Vasilakos John P, Ramakrishna Venky, Wallace Paul K, Keler Tibor
Format: Article
Language:English
Published: BMC 2007-01-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/5/1/5