Effect of N(Epsilon)-(carboxymethyl)lysine on Laboratory Parameters and Its Association with βS Haplotype in Children with Sickle Cell Anemia

The present study aimed to investigate the association of Nε-carboxymethyllysine (CML) with laboratory parameters and βS haplotypes in pediatric sickle cell anemia (SCA) patients with or without hydroxyurea (HU) therapy. We included 55 children with SCA (SCAtotal), where 27 were on HU treatment (SCA...

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Main Authors: Uche Samuel Ndidi, Corynne Stephanie Ahouefa Adanho, Rayra Pereira Santiago, Sètondji Cocou Modeste Alexandre Yahouédéhou, Sânzio Silva Santana, Vitor Valério Mafili, Thassila Nogueira Pitanga, Cleverson Alves Fonseca, Junia Raquel Dutra Ferreira, Elisângela Vitoria Adorno, Isa Menezes Lyra, Adekunle D. Adekile, Cynara Gomes Barbosa, Marilda Souza Goncalves
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2019/1580485